UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                               (AMENDMENT NO. 1)*

                            Protein Design Labs, Inc.
                       ----------------------------------
                                (Name of Issuer)

                                     Common
                       ----------------------------------
                         (Title of Class of Securities)

                                    74369L103
                       ----------------------------------
                                 (CUSIP Number)

     Check the following box if a fee is being paid with this statement /X/. (A
fee is not required only if the filing person: (1) has a previous statement on
file reporting beneficial ownership of more than five percent of the class of
securities described in Item 1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of five percent or less of such class.)
(See Rule 13d-7.)

     *The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior page.

     The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).



CUSIP No. 74369L103                    13G                      Page  2  of   5
                                                                     ---     ---

- --------------------------------------------------------------------------------
1    NAME OF REPORTING PERSONS.
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     Chancellor LGT Asset Management, Inc. (94-2259541) and Chancellor LGT Trust
     Company (52-1576922), as Investment Advisers for various fiduciary accounts
     and LGT Asset Management, Inc. (94-303766) as the holding company for
     Chancellor LGT Asset Management, Inc.
- --------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                        (a)  /X/
                                                                        (b)  / /
- --------------------------------------------------------------------------------
3    SEC USE ONLY

- --------------------------------------------------------------------------------
4    CITIZENSHIP OR PLACE OF ORGANIZATION

          Chancellor LGT Asset Management, Inc. - California
          Chancellor LGT Trust Company - New York
          LGT Asset Management, Inc. - California
- --------------------------------------------------------------------------------
           NUMBER OF               5    SOLE VOTING POWER
            SHARES
         BENEFICIALLY                   - 1,989,500 - shares
           OWNED BY                ---------------------------------------------
             EACH                  6    SHARED VOTING POWER
           REPORTING
          PERSON WITH                           - 0 -
                                   ---------------------------------------------
                                   7    SOLE DISPOSITIVE POWER

                                        - 1,989,500 - shares
                                   ---------------------------------------------
                                   8    SHARED DISPOSITIVE POWER

                                                - 0 -
- -------------------------------------------------------------------------------
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                    - 1,989,500 - shares
- -------------------------------------------------------------------------------
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*


- -------------------------------------------------------------------------------
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                    12.71%
- -------------------------------------------------------------------------------
12   TYPE OF REPORTING PERSON*

                    HC, BK, IA
- -------------------------------------------------------------------------------


CUSIP: 74369L103

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


                                  SCHEDULE 13G


ITEM 1.  SECURITY AND ISSUER

(a)  Protein Design Labs, Inc. (the "Company")

(b)  Address:  2375 Garcia Avenue
               Mountain View, CA 94043

ITEM 2.  IDENTITY AND BACKGROUND

     (a)  This Schedule 13G is being filed by (i) Chancellor LGT Asset
Management, Inc., a California Corporation, whose principal business is
providing investment advisory services to registered investment companies and
institutional investors, (ii) its wholly owned subsidiary, Chancellor LGT Trust
Company, a New York State chartered trust company whose principal business is
providing institutional investment management services and (iii) LGT Asset
Management, Inc., the holding company for Chancellor LGT Asset Management, Inc.
Chancellor LGT Asset Management, Inc. is a wholly owned subsidiary of LGT Asset
Management, Inc.  LGT Asset Management, Inc. is an indirect wholly owned
subsidiary of Liechtenstein Global Trust, AG.  Liechtenstein Global Trust, AG
which has numerous worldwide affiliates is controlled by The Prince of
Liechtenstein Foundation, a parent organization for the various business
enterprises of the Princely Family of Liechtenstein.

     (b)  The address of the principal place of business of Chancellor LGT Asset
Management, Inc. and Chancellor LGT Trust Company is: 1166 Avenue of the
Americas, New York, New York 10036.  The address of the principal place of the
holding company, LGT Asset Management, Inc. is 50 California Street, San
Francisco, CA  94111

     (c)  Chancellor LGT Asset Management, Inc. is a California Corporation.
Chancellor LGT Trust Company is a New York State chartered trust company.  LGT
Asset Management, Inc. is a California Corporation

     (d)  Common Stock

     (e)  CUSIP Number 74369L103

ITEM 3.  IF THIS STATEMENT IS FILED PURSUANT TO RULE 13d-1(b) OR 13d-2(b), CHECK
WHETHER THE PERSON FILING IS A:

     (h)   X   Group, in accordance with Rule 13d-1(b)(i)(ii)(H).
          ---



ITEM 4.  OWNERSHIP

     (a)  For the month ended December 31, 1996, the aggregate number of shares
of the Company's common stock beneficially owned by Chancellor LGT Asset
Management, Inc. and Chancellor LGT Trust Company, as investment advisers for
various fiduciary accounts and LGT Asset Management, Inc., as the holding
company is 1,989,500 shares.

     (b)  Percent of Class: 12.71% based upon 15,654,000 shares outstanding.

     (c)  Chancellor LGT Asset Management, Inc. and Chancellor LGT Trust
Company, as investment advisers for various fiduciary accounts, have sole power
to vote or to direct to vote, and sole power to dispose of or to direct the
disposition of, all of the shares reported in this statement.  Chancellor LGT
Asset Management, Inc. is a wholly owned subsidiary of LGT Asset Management,
Inc.  LGT Asset Management, Inc. is an indirect wholly owned subsidiary of
Liechtenstein Global Trust, AG.  Liechtenstein Global Trust, AG which has
numerous worldwide affiliates is controlled by The Prince of Liechtenstein
Foundation, a parent organization for the various business enterprises of the
Princely Family of Liechtenstein.

ITEM 5.  OWNERSHIP OF FIVE PERCENT OR LESS

     Not applicable

ITEM 6.  OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

     Chancellor LGT Asset Management, Inc. and Chancellor LGT Trust Company are
investment advisers for various fiduciary accounts which are entitled to receipt
of dividends and to proceeds of the sale of the shares reported in this
Statement.  The ownership interest of any such account does not relate to more
than five percent of the Common Stock.

ITEM 7.  IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
SECURITIES BEING REPORTED BY THE PARENT HOLDING COMPANY

     Not applicable.

ITEM 8.  IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF A GROUP

     See attached Exhibit I

ITEM 9.  NOTICE OF DISSOLUTION OF GROUP

     Not applicable.



ITEM 10.  CERTIFICATION

     By signing below I certify that to the best of my knowledge and belief, the
securities referred to above were acquired in the ordinary course of business
and were not acquired for the purpose of and do not have the effect of changing
or influencing the control of the issuer of such securities and were not
acquired in connection with or as a participant in any transaction having such
purposes or effect.

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.


Date:  February 7, 1997


Signatures:

               Chancellor LGT Asset Management, Inc.
                    as Investment Adviser


               By:
                  ----------------------------------
                    James R. Tufts, III



               Chancellor LGT Trust Company
                    as Investment Adviser


               By:
                  ----------------------------------
                    James R. Tufts, III



               LGT Asset Management, Inc.
                    as Holding Company


               By:
                  ----------------------------------
                    James R. Tufts, III





                                    EXHIBIT I



ITEM 3

     (b)   X   Bank as defined in Section 3(a)(b) of the Act
          ---
               Chancellor LGT Trust Company

     (c)   X   Investment Adviser registered under Section 203 of the Investment
          ---
Advisers Act of 1940.

               Chancellor LGT Asset Management, Inc.