UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*

                            PROTEIN DESIGN LABS, INC.
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                          Common Stock, $0.01 Par Value
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    74369L103
                                 --------------
                                 (CUSIP Number)


                                  July 30, 1998
                      ------------------------------------
                      (Date of Event which Requires Filing
                               of this Statement)



Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

                  [  ]      Rule 13d-1(b)
                  [X ]      Rule 13d-1(c)
                  [  ]      Rule 13d-1(d)



  *The remainder of this cover page shall be filled out for a reporting person's
  initial  filing on this form with respect to the subject class of  securities,
  and for any subsequent amendment containing  information which would alter the
  disclosures provided in a prior cover page.

  The  information  required  on the  remainder  of this cover page shall not be
  deemed to be "filed" for the purpose of Section 18 of the Securities  Exchange
  Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
  the Act but shall be subject to all other provisions of the Act (however,  see
  the Notes).


                               Page 1 of 11 pages



CUSIP No.  74369L103                         13G         Page  2   of  11  Pages
        --------------
- ---------- ---------------------------------------------------------------------
        1  NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Soros Fund Management LLC
- ---------- ---------------------------------------------------------------------
        2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                      (a)[ ]

                                                                      (b)[X]
- ---------- ---------------------------------------------------------------------
        3  SEC USE ONLY

- ---------- ---------------------------------------------------------------------
        4  CITIZENSHIP OR PLACE OF ORGANIZATION

           DELAWARE
- -------------------- ------ ----------------------------------------------------
                         5  SOLE VOTING POWER

                            881,700
                     ------ ----------------------------------------------------
     NUMBER OF           6  SHARED VOTING POWER
      SHARES
   BENEFICIALLY             -0-
     OWNED BY
                     ------ ----------------------------------------------------
       EACH              7  SOLE DISPOSITIVE POWER
     REPORTING
      PERSON                881,700
       WITH
                     ------ ----------------------------------------------------
                         8  SHARED DISPOSITIVE POWER

                            -0-
- ---------- ---------------------------------------------------------------------
        9  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           881,700
- ---------- ---------------------------------------------------------------------
       10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                 [ ]
- ---------- ---------------------------------------------------------------------
       11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

           4.76%
- ---------- ---------------------------------------------------------------------
       12  TYPE OF REPORTING PERSON*

           OO, IA
- ---------- ---------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!







CUSIP No.  74369L103                         13G         Page  3   of  11  Pages
        --------------
- ---------- ---------------------------------------------------------------------
        1  NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           George Soros    (in the capacity described herein)
- ---------- ---------------------------------------------------------------------
        2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                               (a) [ ]
                                                               (b) [X]
- ---------- ---------------------------------------------------------------------
        3  SEC USE ONLY

- ---------- ---------------------------------------------------------------------
        4  CITIZENSHIP OR PLACE OF ORGANIZATION

           UNITED STATES
- ---------- ---------------------------------------------------------------------
                         5  SOLE VOTING POWER

                            -0-
                     ------ ----------------------------------------------------
     NUMBER OF           6  SHARED VOTING POWER
      SHARES
   BENEFICIALLY             881,700
     OWNED BY
                     ------ ----------------------------------------------------
       EACH              7  SOLE DISPOSITIVE POWER
     REPORTING
      PERSON                -0-
       WITH
                     ------ ----------------------------------------------------
                         8  SHARED DISPOSITIVE POWER

                            881,700
- ---------- ---------------------------------------------------------------------
        9  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           881,700
- ---------- ---------------------------------------------------------------------
       10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
                                                            [ ]
- ---------- ---------------------------------------------------------------------
       11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

           4.76%
- ---------- ---------------------------------------------------------------------
       12  TYPE OF REPORTING PERSON*

           IA
- ---------- ---------------------------------------------------------------------


                      *SEE INSTRUCTION BEFORE FILLING OUT!








CUSIP No.  74369L103                         13G         Page  4   of  11  Pages
        --------------
- ---------- ---------------------------------------------------------------------
        1  NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Stanley F. Druckenmiller    (in the capacity described herein)
- ---------- ---------------------------------------------------------------------
        2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                       (a) [ ]

                                                                       (b) [X]
- ---------- ---------------------------------------------------------------------
        3  SEC USE ONLY

- ---------- ---------------------------------------------------------------------
        4  CITIZENSHIP OR PLACE OF ORGANIZATION

           UNITED STATES
- ---------- ---------------------------------------------------------------------
                         5  SOLE VOTING POWER

                            -0-
                     ------ ----------------------------------------------------
     NUMBER OF           6  SHARED VOTING POWER
      SHARES
   BENEFICIALLY             881,700
     OWNED BY
                     ------ ----------------------------------------------------
       EACH              7  SOLE DISPOSITIVE POWER
     REPORTING
      PERSON                -0-
       WITH
                     ------ ----------------------------------------------------
                         8  SHARED DISPOSITIVE POWER

                            881,700
- ---------- ---------------------------------------------------------------------
        9  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           881,700
- ---------- ---------------------------------------------------------------------
       10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
                                                                 [ ]
- ---------- ---------------------------------------------------------------------
       11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

           4.76%
- ---------- ---------------------------------------------------------------------
       12  TYPE OF REPORTING PERSON*

           IA
- ---------- ---------------------------------------------------------------------


                      *SEE INSTRUCTION BEFORE FILLING OUT!









CUSIP No.  74369L103                         13G         Page  5   of  11  Pages
        --------------
- ---------- ---------------------------------------------------------------------
        1  NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Duquesne Capital Management, L.L.C.
- ---------- ---------------------------------------------------------------------
        2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                    (a)[ ]

                                                                    (b)[X]
- ---------- ---------------------------------------------------------------------
        3  SEC USE ONLY

- ---------- ---------------------------------------------------------------------
        4  CITIZENSHIP OR PLACE OF ORGANIZATION

           PENNSYLVANIA
- ---------- ---------------------------------------------------------------------
                         5  SOLE VOTING POWER

                            -0-
                     ------ ----------------------------------------------------
     NUMBER OF           6  SHARED VOTING POWER
      SHARES
   BENEFICIALLY             -0-
     OWNED BY
                     ------ ----------------------------------------------------
       EACH              7  SOLE DISPOSITIVE POWER
     REPORTING
      PERSON                -0-
       WITH
                     ------ ----------------------------------------------------
                         8  SHARED DISPOSITIVE POWER

                            -0-
- ---------- ---------------------------------------------------------------------
        9  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           -0-
- ---------- ---------------------------------------------------------------------
       10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

                                                            [X]
- ---------- ---------------------------------------------------------------------
       11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

           0.0%
- ---------- ---------------------------------------------------------------------
       12  TYPE OF REPORTING PERSON*

           OO, IA
- ---------- ---------------------------------------------------------------------

                      *SEE INSTRUCTION BEFORE FILLING OUT!









Item 1(a)                       Name of Issuer:
                                ---------------

                                Protein Design Labs, Inc. (the "Issuer")

Item 1(b)                       Address of Issuer's Principal Executive Offices:
                                ------------------------------------------------

                                2375 Garcia Avenue
                                Mountain View, California 94043

Items 2(a)                      Name of Person Filing:
                                ----------------------

                                This  Statement  is  filed on  behalf  of the
                                following persons (collectively, the
                                "Reporting Persons"):

                                 i)   Soros Fund Management LLC, a Delaware
                                      limited liability company ("SFM LLC");

                                 ii)  Mr. George Soros ("Mr. Soros");

                                iii)  Mr. Stanley F. Druckenmiller
                                      ("Mr. Druckenmiller"); and

                                 iv)  Duquesne Capital Management, L.L.C., a
                                      Pennsylvania limited liability company
                                      ("Duquesne LLC").

                                    This Statement relates to Shares (as defined
                                    herein)  held for the  accounts  of  Quantum
                                    Partners and the Duquesne LLC Clients  (each
                                    as  defined  herein).  SFM LLC,  a  Delaware
                                    limited   liability   company,   serves   as
                                    principal   investment  manager  to  Quantum
                                    Partners  LDC,  a  Cayman  Islands  exempted
                                    duration company  ("Quantum  Partners") and,
                                    as  such,   has  been   granted   investment
                                    discretion   over   portfolio   investments,
                                    including  the Shares,  held for the account
                                    of  Quantum  Partners.   Mr.  Soros  is  the
                                    Chairman of SFM LLC.  Mr.  Druckenmiller  is
                                    the Lead  Portfolio  Manager and a Member of
                                    the  Management  Committee  of SFM LLC.  Mr.
                                    Druckenmiller  also owns a 75%  interest in,
                                    and is the sole managing member of, Duquesne
                                    LLC, an investment advisory firm that serves
                                    as a discretionary  investment  advisor to a
                                    limited number of institutional clients (the
                                    "Duquesne LLC Clients").


                               Page 6 of 11 pages






Item 2(b)                          Address of Principal Business Office:
                                   -------------------------------------

                                   The address of the principal business office
                                   of each of SFM LLC, Mr. Soros and Mr.
                                   Druckenmiller is 888 Seventh Avenue, 33rd
                                   Floor, New York, NY 10106.

                                   The address of the principal  business office
                                   of  Duquesne  LLC is  2579  Washington  Road,
                                   Suite 322, Pittsburgh, Pennsylvania
                                   15241-2591.

Item 2(c)                          Citizenship:
                                   ------------

                                  i)       SFM LLC is a Delaware limited
                                            liability company;
                                  ii)      Mr. Soros is a United States citizen;
                                  iii)     Mr. Druckenmiller is a United States
                                            citizen; and
                                  iv)      Duquesne LLC is a Pennsylvania
                                            limited liability company.

Item 2(d)                          Title of Class of Securities:
                                   -----------------------------

                                   Common Stock, par value $0.01 per share (the
                                   "Shares")

Item 2(e)                          CUSIP Number:
                                   -------------

                                   74369L103

Item 3                             Not Applicable

Item 4.                            Ownership:
                                   ----------

Item 4(a)                          Amount Beneficially Owned:
                                   --------------------------

                                   As of August 6, 1998,  SFM LLC, Mr. Soros and
                                   Mr.  Druckenmiller  may be  deemed  to be the
                                   beneficial  owner of the 881,700  Shares held
                                   for the account of Quantum Partners.

                                   As of August 6, 1998,  Duquesne  LLC does not
                                   beneficially own any Shares,  as there are no
                                   Shares  being  held for the  accounts  of the
                                   Duquesne LLC Clients.

Item 4(b)                          Percent of Class:
                                   -----------------

                                   i)  The number of Shares of which SFM LLC,
                                   Mr. Soros and Mr. Druckenmiller may be deemed
                                   to be the beneficial owner constitutes
                                   approximately

                               Page 7 of 11 pages




                                   4.76% of the total number of Shares
                                   outstanding.

                                   ii) The number of Shares  which  Duquesne LLC
                                   beneficially  owns constitutes 0.0% the total
                                   number of Shares outstanding.


Item 4(c)                          Number of shares as to which such person has:
                                   ---------------------------------------------

                                   SFM LLC
                                   -------

                                   (i)   Sole power to vote or to direct the
                                         vote: 881,700

                                   (ii)  Shared power to vote or to direct the
                                         vote:  -0-

                                   (iii) Sole power to dispose or to direct the
                                         disposition of:  881,700

                                   (iv)  Shared power to dispose or to direct
                                         the disposition of:  -0-

                                   Mr. Soros
                                   ---------

                                   (i)    Sole power to vote or to direct the
                                          vote:  -0-

                                   (ii)   Shared power to vote or to direct the
                                          vote:  881,700

                                   (iii)  Sole power to dispose or to direct the
                                          disposition of:  -0-

                                   (iv)   Shared power to dispose or to direct
                                          the disposition of: 881,700

                                   Mr. Druckenmiller
                                   -----------------

                                   (i)    Sole power to vote or to direct the
                                          vote:  -0-

                                   (ii)   Shared power to vote or to direct the
                                          vote:  881,700

                                   (iii)  Sole power to dispose or to direct the
                                          disposition of:  -0-

                                   (iv)   Shared power to dispose or to direct
                                          the disposition of:  881,700



                               Page 8 of 11 pages





                                   Duquesne LLC
                                   ------------

                                   (i)    Sole power to vote or to direct the
                                          vote:  -0-

                                   (ii)   Shared power to vote or to direct the
                                          vote:  -0-

                                   (iii)  Sole power to dispose or to direct the
                                          disposition of:  -0-

                                   (iv)   Shared power to dispose or to direct
                                          the disposition of:  -0-

Item 5                             Ownership of Five Percent or Less of a Class:
                                   -------------------------------------------- 

                                   If this Statement is being filed to report
the fact that as of the date hereof each of the Reporting  Persons  has  ceased
to be the  beneficial  owner of more  than five percent of a class of
securities, check the following:        [X]

Item 6                             Ownership of More than Five Percent on Behalf
                                   of Another Person:
                                   ---------------------------------------------

                                   The   shareholders   of   Quantum   Partners,
                                   including  Quantum Fund N.V.,  a  Netherlands
                                   Antilles   company,   have   the   right   to
                                   participate in the receipt of dividends from,
                                   or proceeds from the sale of, the Shares held
                                   for  the  account  of  Quantum   Partners  in
                                   accordance with their ownership  interests in
                                   Quantum Partners.

                                   The  Duquesne  LLC Clients  have the right to
                                   participate in the receipt of dividends from,
                                   or  proceeds  from the sale of,  the  Shares,
                                   that were held for their accounts.

                                   Each  of SFM  LLC  and  Mr.  Soros  expressly
                                   disclaims  beneficial ownership of any Shares
                                   that  were  held  for  the  accounts  of  the
                                   Duquesne LLC Clients.  Duquesne LLC expressly
                                   disclaims  beneficial ownership of any Shares
                                   held for the account of Quantum Partners.

Item 7                             Identification and Classification of the
                                   ----------------------------------------
                                   Subsidiary Which Acquired the Security Being
                                   --------------------------------------------
                                   Reported on By the Parent Holding Company:
                                   ----------------------------------------- 

                                   Not Applicable


                               Page 9 of 11 pages


Item 8                             Identification and Classification of Members
                                   --------------------------------------------
                                   of the Group:
                                   -------------

                                    Not Applicable


Item 9                              Notice of Dissolution of Group:
                                    ------------------------------ 

                                    Not Applicable

Item 10                             Certification:
                                    --------------

         By signing below each signatory  certifies that, to the best of his/its
knowledge and belief, the securities referred to above were not acquired and are
not held for the purpose of or with the effect of changing  or  influencing  the
control of the Issuer of the  securities  and were not acquired and are not held
in connection with or as a participant in any transaction having that purpose or
effect.


                               Page 10 of 11 pages




                                    SIGNATURE

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.



Dated: August 6, 1998      SOROS FUND MANAGEMENT LLC


                           By:   /s/ Michael C. Neus
                                 Michael C. Neus
                                 Assistant General Counsel


Dated: August 6, 1998      GEORGE SOROS


                            By:   /s/ Michael C. Neus
                                  Michael C. Neus
                                  Attorney-in-Fact


Dated: August 6, 1998      STANLEY F. DRUCKENMILLER


                            By:  /s/ Michael C. Neus
                                 Michael C. Neus
                                 Attorney-in-Fact


Dated: August 6, 1998      DUQUESNE CAPITAL MANAGEMENT, L.L.C.


                           By:  /s/ Gerald Kerner
                                Gerald Kerner
                                Managing Director


                               Page 11 of 11 pages